We present SpiCO, a new modeling and simulation language for systems biology. SpiCO is based on the stochastic π-calculus. It supports higher level modeling via multi-profile con...
ct This paper provides an overview of the WarpIV Simulation Kernel that was designed to be an initial implementation of the Standard Simulation Architecture (SSA). WarpIV is the ne...
Just as electronic systems implement computation in terms of voltage (energy per unit charge), molecular systems compute in terms of chemical concentrations (molecules per unit vo...
A simplified electrodiffusion model for rectangular current pulses in ionic channels of biological membranes is presented. Numerical simulations and a dynamical systems analysis of...
Carl L. Gardner, Joseph W. Jerome, Robert S. Eisen...
We describe our experiences with the process of designing a domain-specific language (DSL) and corresponding model transformations. The simultaneous development of the language an...
Marcel van Amstel, Mark van den Brand, Luc Engelen