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RECOMB
2005
Springer
15 years 10 months ago
Very Low Power to Detect Asymmetric Divergence of Duplicated Genes
Abstract. Asymmetric functional divergence of paralogues is a key aspect of the traditional model of evolution following duplication. If one gene continues to perform the ancestral...
Cathal Seoighe, Konrad Scheffler
CDC
2010
IEEE
141views Control Systems» more  CDC 2010»
14 years 4 months ago
Hybrid moment computation algorithm for biochemical reaction networks
Moment computation is essential to the analysis of stochastic kinetic models of biochemical reaction networks. It is often the case that the moment evolution, usually the first and...
Yun-Bo Zhao, Jongrae Kim, João Pedro Hespan...
BIOSYSTEMS
2008
72views more  BIOSYSTEMS 2008»
14 years 9 months ago
The manipulation of calcium oscillations by harnessing self-organisation
This paper investigates how self-organisation might be harnessed for the manipulation and control of calcium oscillations. Calcium signalling mechanisms are responsible for a numb...
Cristina Costa Santini, Andy M. Tyrrell
JCB
2006
125views more  JCB 2006»
14 years 9 months ago
Hypothesis Generation in Signaling Networks
Biological signaling networks comprise the chemical processes by which cells detect and respond to changes in their environment. Such networks have been implicated in the regulati...
Derek A. Ruths, Luay Nakhleh, M. Sriram Iyengar, S...
BMCBI
2010
172views more  BMCBI 2010»
14 years 9 months ago
Comparison of evolutionary algorithms in gene regulatory network model inference
Background: The evolution of high throughput technologies that measure gene expression levels has created a data base for inferring GRNs (a process also known as reverse engineeri...
Alina Sîrbu, Heather J. Ruskin, Martin Crane