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    BIBM
    2008
    IEEE
    112views Bioinformatics» more  BIBM 2008»
    Predicting Protective Linear B-Cell Epitopes Using Evolutionary Information
    15 years 4 months ago
    Predicting Protective Linear B-Cell Epitopes Using Evolutionary Information
    Download  www.cs.iastate.edu
    Mapping B-cell epitopes plays an important role in vaccine design, immunodiagnostic tests, and antibody production. Because the experimental determination of B-cell epitopes is ti...
    Yasser El-Manzalawy, Drena Dobbs, Vasant Honavar
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    BMCBI
    2010
    109views more  BMCBI 2010»
    Prediction of the binding affinities of peptides to class II MHC using a regularized thermodynamic model
    14 years 9 months ago
    Prediction of the binding affinities of peptides to class II MHC using a regularized thermodynamic model
    Download  www.biomedcentral.com
    Background: The binding of peptide fragments of extracellular peptides to class II MHC is a crucial event in the adaptive immune response. Each MHC allotype generally binds a dist...
    Andrew J. Bordner, Hans D. Mittelmann
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    BMCBI
    2006
    111views more  BMCBI 2006»
    PepDist: A New Framework for Protein-Peptide Binding Prediction based on Learning Peptide Distance Functions
    14 years 9 months ago
    PepDist: A New Framework for Protein-Peptide Binding Prediction based on Learning Peptide Distance Functions
    Download  www.biomedcentral.com
    Background: Many different aspects of cellular signalling, trafficking and targeting mechanisms are mediated by interactions between proteins and peptides. Representative examples...
    Tomer Hertz, Chen Yanover
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    IDEAL
    2005
    Springer
    124views Intelligent Agents» more  IDEAL 2005»
    Predictive Vaccinology: Optimisation of Predictions Using Support Vector Machine Classifiers
    15 years 3 months ago
    Predictive Vaccinology: Optimisation of Predictions Using Support Vector Machine Classifiers
    Download  poincare.matf.bg.ac.rs
    Promiscuous human leukocyte antigen (HLA) binding peptides are ideal targets for vaccine development. Existing computational models for prediction of promiscuous peptides used hidd...
    Ivana Bozic, Guanglan Zhang, Vladimir Brusic
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    BMCBI
    2010
    110views more  BMCBI 2010»
    MultiRTA: A simple yet reliable method for predicting peptide binding affinities for multiple class II MHC allotypes
    14 years 9 months ago
    MultiRTA: A simple yet reliable method for predicting peptide binding affinities for multiple class II MHC allotypes
    Download  www.biomedcentral.com
    Background: The binding of peptide fragments of antigens to class II MHC is a crucial step in initiating a helper T cell immune response. The identification of such peptide epitop...
    Andrew J. Bordner, Hans D. Mittelmann
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