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BMCBI
2011
14 years 3 months ago
Gene set analysis for longitudinal gene expression data
Background: Gene set analysis (GSA) has become a successful tool to interpret gene expression profiles in terms of biological functions, molecular pathways, or genomic locations. ...
Ke Zhang, Haiyan Wang, Arne C. Bathke, Solomon W. ...
BMCBI
2008
115views more  BMCBI 2008»
14 years 12 months ago
Genome-scale cluster analysis of replicated microarrays using shrinkage correlation coefficient
Background: Currently, clustering with some form of correlation coefficient as the gene similarity metric has become a popular method for profiling genomic data. The Pearson corre...
Jianchao Yao, Chunqi Chang, Mari L. Salmi, Yeung S...
BMCBI
2010
154views more  BMCBI 2010»
14 years 12 months ago
Candidate gene prioritization by network analysis of differential expression using machine learning approaches
Background: Discovering novel disease genes is still challenging for diseases for which no prior knowledge - such as known disease genes or disease-related pathways - is available...
Daniela Nitsch, Joana P. Gonçalves, Fabian ...
BMCBI
2008
97views more  BMCBI 2008»
14 years 12 months ago
Quantitative analysis of numerical solvers for oscillatory biomolecular system models
Background: This article provides guidelines for selecting optimal numerical solvers for biomolecular system models. Because various parameters of the same system could have drast...
Chang F. Quo, May D. Wang
BMCBI
2004
154views more  BMCBI 2004»
14 years 11 months ago
Base-By-Base: Single nucleotide-level analysis of whole viral genome alignments
Background: With ever increasing numbers of closely related virus genomes being sequenced, it has become desirable to be able to compare two genomes at a level more detailed than ...
Ryan Brodie, Alex J. Smith, Rachel L. Roper, Vasil...