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» Essentiality and damage in metabolic networks
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BMCBI
2011
12 years 10 months ago
FFCA: a feasibility-based method for flux coupling analysis of metabolic networks
Background: Flux coupling analysis (FCA) is a useful method for finding dependencies between fluxes of a metabolic network at steady-state. FCA classifies reactions into subsets (...
László Dávid, Sayed-Amir Mara...
BMCBI
2007
93views more  BMCBI 2007»
13 years 6 months ago
The topology of metabolic isotope labeling networks
Background: Metabolic Flux Analysis (MFA) based on isotope labeling experiments (ILEs) is a widely established tool for determining fluxes in metabolic pathways. Isotope labeling ...
Michael Weitzel, Wolfgang Wiechert, Katharina N&ou...
BMCBI
2010
86views more  BMCBI 2010»
13 years 6 months ago
Reaction graph kernels predict EC numbers of unknown enzymatic reactions in plant secondary metabolism
Background: Understanding of secondary metabolic pathway in plant is essential for finding druggable candidate enzymes. However, there are many enzymes whose functions are not yet...
Hiroto Saigo, Masahiro Hattori, Hisashi Kashima, K...
NAR
2008
103views more  NAR 2008»
13 years 6 months ago
STITCH: interaction networks of chemicals and proteins
The knowledge about interactions between proteins and small molecules is essential for the understanding of molecular and cellular functions. However, information on such interact...
Michael Kuhn 0004, Christian von Mering, Monica Ca...
DISCEX
2003
IEEE
13 years 11 months ago
Willow System Demonstration
Dealing with damage that arises during operation of networked information systems is essential if such systems are to provide the dependability required by modern critical applica...
John C. Knight, Jonathan Hill, Philip E. Varner, P...