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BMCBI
2008
93views more  BMCBI 2008»
14 years 9 months ago
MPDA: Microarray pooled DNA analyzer
Background: Microarray-based pooled DNA experiments that combine the merits of DNA pooling and gene chip technology constitute a pivotal advance in biotechnology. This new techniq...
Hsin-Chou Yang, Mei-Chu Huang, Ling-Hui Li, Chien-...
IJAR
2006
125views more  IJAR 2006»
14 years 9 months ago
Computing best-possible bounds for the distribution of a sum of several variables is NP-hard
In many real-life situations, we know the probability distribution of two random variables x1 and x2, but we have no information about the correlation between x1 and x2; what are ...
Vladik Kreinovich, Scott Ferson
BIOINFORMATICS
2005
72views more  BIOINFORMATICS 2005»
14 years 9 months ago
Use of within-array replicate spots for assessing differential expression in microarray experiments
Motivation. Spotted arrays are often printed with probes in duplicate or triplicate, but current methods for assessing differential expression are not able to make full use of the...
Gordon K. Smyth, Joëlle Michaud, Hamish S. Sc...
BMCBI
2005
152views more  BMCBI 2005»
14 years 9 months ago
Improved profile HMM performance by assessment of critical algorithmic features in SAM and HMMER
Background: Profile hidden Markov model (HMM) techniques are among the most powerful methods for protein homology detection. Yet, the critical features for successful modelling ar...
Markus Wistrand, Erik L. L. Sonnhammer
PRL
2010
149views more  PRL 2010»
14 years 4 months ago
Adaptive linear models for regression: Improving prediction when population has changed
The general setting of regression analysis is to identify a relationship between a response variable Y and one or several explanatory variables X by using a learning sample. In a ...
Charles Bouveyron, Julien Jacques