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» Estimating the Distance to a Monotone Function
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ETVC
2008
13 years 8 months ago
Statistical Computing on Manifolds: From Riemannian Geometry to Computational Anatomy
Computational anatomy is an emerging discipline that aims at analyzing and modeling the individual anatomy of organs and their biological variability across a population. The goal ...
Xavier Pennec
BMCBI
2008
114views more  BMCBI 2008»
13 years 6 months ago
Dinucleotide controlled null models for comparative RNA gene prediction
Background: Comparative prediction of RNA structures can be used to identify functional noncoding RNAs in genomic screens. It was shown recently by Babak et al. [BMC Bioinformatic...
Tanja Gesell, Stefan Washietl
CORR
2011
Springer
167views Education» more  CORR 2011»
13 years 1 months ago
Fast global convergence of gradient methods for high-dimensional statistical recovery
Many statistical M-estimators are based on convex optimization problems formed by the weighted sum of a loss function with a norm-based regularizer. We analyze the convergence rat...
Alekh Agarwal, Sahand Negahban, Martin J. Wainwrig...
BMCBI
2011
12 years 10 months ago
A mutation degree model for the identification of transcriptional regulatory elements
Background: Current approaches for identifying transcriptional regulatory elements are mainly via the combination of two properties, the evolutionary conservation and the overrepr...
Changqing Zhang, Jin Wang, Xu Hua, Jinggui Fang, H...
JCC
2011
154views more  JCC 2011»
12 years 9 months ago
Can we trust docking results? Evaluation of seven commonly used programs on PDBbind database
: Docking is one of the most commonly used techniques in drug design. It is used for both identifying correct poses of a ligand in the binding site of a protein as well as for the ...
Dariusz Plewczynski, Michal Lazniewski, Rafal Augu...