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» Estimation of the Rate-Distortion Function
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BMCBI
2006
103views more  BMCBI 2006»
14 years 11 months ago
Domain-based small molecule binding site annotation
Background: Accurate small molecule binding site information for a protein can facilitate studies in drug docking, drug discovery and function prediction, but small molecule bindi...
Kevin A. Snyder, Howard J. Feldman, Michel Dumonti...
BMCBI
2006
143views more  BMCBI 2006»
14 years 11 months ago
IsoSVM - Distinguishing isoforms and paralogs on the protein level
Background: Recent progress in cDNA and EST sequencing is yielding a deluge of sequence data. Like database search results and proteome databases, this data gives rise to inferred...
Michael Spitzer, Stefan Lorkowski, Paul Cullen, Al...
BMCBI
2006
94views more  BMCBI 2006»
14 years 11 months ago
Fly-DPI: database of protein interactomes for D. melanogaster in the approach of systems biology
Background: Proteins control and mediate many biological activities of cells by interacting with other protein partners. This work presents a statistical model to predict protein ...
Chung-Yen Lin, Shu-Hwa Chen, Chi-Shiang Cho, Chia-...
BMCBI
2006
103views more  BMCBI 2006»
14 years 11 months ago
Statistical inference of chromosomal homology based on gene colinearity and applications to Arabidopsis and rice
Background: The identification of chromosomal homology will shed light on such mysteries of genome evolution as DNA duplication, rearrangement and loss. Several approaches have be...
Xiyin Wang, Xiaoli Shi, Zhe Li, Qihui Zhu, Lei Kon...
BMCBI
2006
126views more  BMCBI 2006»
14 years 11 months ago
Differential prioritization between relevance and redundancy in correlation-based feature selection techniques for multiclass ge
Background: Due to the large number of genes in a typical microarray dataset, feature selection looks set to play an important role in reducing noise and computational cost in gen...
Chia Huey Ooi, Madhu Chetty, Shyh Wei Teng