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BMCBI
2010
117views more  BMCBI 2010»
14 years 11 months ago
Beyond rotamers: a generative, probabilistic model of side chains in proteins
Background: Accurately covering the conformational space of amino acid side chains is essential for important applications such as protein design, docking and high resolution stru...
Tim Harder, Wouter Boomsma, Martin Paluszewski, Je...
BMCBI
2010
106views more  BMCBI 2010»
14 years 11 months ago
Predicting MHC class I epitopes in large datasets
Background: Experimental screening of large sets of peptides with respect to their MHC binding capabilities is still very demanding due to the large number of possible peptide seq...
Kirsten Roomp, Iris Antes, Thomas Lengauer
BMCBI
2010
97views more  BMCBI 2010»
14 years 11 months ago
SeqRate: sequence-based protein folding type classification and rates prediction
Background: Protein folding rate is an important property of a protein. Predicting protein folding rate is useful for understanding protein folding process and guiding protein des...
Guan Ning Lin, Zheng Wang, Dong Xu, Jianlin Cheng
BMCBI
2008
89views more  BMCBI 2008»
14 years 11 months ago
R/parallel - speeding up bioinformatics analysis with R
Background: R is the preferred tool for statistical analysis of many bioinformaticians due in part to the increasing number of freely available analytical methods. Such methods ca...
Gonzalo Vera, Ritsert C. Jansen, Remo Suppi
BMCBI
2010
128views more  BMCBI 2010»
14 years 11 months ago
VIGOR, an annotation program for small viral genomes
Background: The decrease in cost for sequencing and improvement in technologies has made it easier and more common for the re-sequencing of large genomes as well as parallel seque...
Shiliang Wang, Jaideep P. Sundaram, David Spiro