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BMCBI
2007
97views more  BMCBI 2007»
15 years 4 months ago
SIRAC: Supervised Identification of Regions of Aberration in aCGH datasets
Background: Array comparative genome hybridization (aCGH) provides information about genomic aberrations. Alterations in the DNA copy number may cause the cell to malfunction, lea...
Carmen Lai, Hugo M. Horlings, Marc J. van de Vijve...
BMCBI
2008
104views more  BMCBI 2008»
15 years 4 months ago
ReRep: Computational detection of repetitive sequences in genome survey sequences (GSS)
Background: Genome survey sequences (GSS) offer a preliminary global view of a genome since, unlike ESTs, they cover coding as well as non-coding DNA and include repetitive region...
Thomas D. Otto, Leonardo H. F. Gomes, Marcelo Alve...
BMCBI
2008
124views more  BMCBI 2008»
15 years 4 months ago
A probe-treatment-reference (PTR) model for the analysis of oligonucleotide expression microarrays
Background: Microarray pre-processing usually consists of normalization and summarization. Normalization aims to remove non-biological variations across different arrays. The norm...
Huanying Ge, Chao Cheng, Lei M. Li
BMCBI
2008
144views more  BMCBI 2008»
15 years 4 months ago
Pep-3D-Search: a method for B-cell epitope prediction based on mimotope analysis
Background: The prediction of conformational B-cell epitopes is one of the most important goals in immunoinformatics. The solution to this problem, even if approximate, would help...
Yanxin Huang, Yongli Bao, Shu Yan Guo, Yan Wang, C...
BMCBI
2008
124views more  BMCBI 2008»
15 years 4 months ago
Literature-aided meta-analysis of microarray data: a compendium study on muscle development and disease
Background: Comparative analysis of expression microarray studies is difficult due to the large influence of technical factors on experimental outcome. Still, the identified diffe...
Rob Jelier, Peter A. C. 't Hoen, Ellen Sterrenburg...
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