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122
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BMCBI
2010
110views more  BMCBI 2010»
15 years 2 months ago
On the use of resampling tests for evaluating statistical significance of binding-site co-occurrence
Background: In eukaryotes, most DNA-binding proteins exert their action as members of large effector complexes. The presence of these complexes are revealed in high-throughput gen...
David S. Huen, Steven Russell
127
Voted
RECOMB
2006
Springer
16 years 2 months ago
Genome-Wide Discovery of Modulators of Transcriptional Interactions in Human B Lymphocytes
Abstract. Transcriptional interactions in a cell are modulated by a variety of mechanisms that prevent their representation as pure pairwise interactions between a transcription fa...
Kai Wang, Ilya Nemenman, Nilanjana Banerjee, Adam ...
VLDB
2004
ACM
127views Database» more  VLDB 2004»
16 years 2 months ago
Querying high-dimensional data in single-dimensional space
In this paper, we propose a new tunable index scheme, called iMinMax(), that maps points in highdimensional spaces to single-dimensional values determined by their maximum or minim...
Cui Yu, Stéphane Bressan, Beng Chin Ooi, Kian-Lee...
216
Voted
KCAP
2011
ACM
14 years 5 months ago
Let's agree to disagree: on the evaluation of vocabulary alignment
Gold standard mappings created by experts are at the core of alignment evaluation. At the same time, the process of manual evaluation is rarely discussed. While the practice of ha...
Anna Tordai, Jacco van Ossenbruggen, Guus Schreibe...
126
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INFOCOM
2007
IEEE
15 years 8 months ago
Multivariate Online Anomaly Detection Using Kernel Recursive Least Squares
— High-speed backbones are regularly affected by various kinds of network anomalies, ranging from malicious attacks to harmless large data transfers. Different types of anomalies...
Tarem Ahmed, Mark Coates, Anukool Lakhina