Background: The detection of conserved motifs in promoters of orthologous genes (phylogenetic footprints) has become a common strategy to predict cis-acting regulatory elements. S...
Over the past decade, software architecture research has emerged as the principled study of the overall structure of software systems, especially the relations among subsystems an...
Separation of concerns has been central to software engineering for decades, yet its many advantages are still not fully realized. A key reason is that traditional modularization ...
Peri L. Tarr, William H. Harrison, Harold Ossher, ...
Background: Transposable elements are abundant in eukaryotic genomes and it is believed that they have a significant impact on the evolution of gene and chromosome structure. Whil...
Recently, more attention is paid to the researches and practices on how to use software architecture in software maintenance and evolution to reduce their complexity and cost. The ...