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BMCBI
2007
135views more  BMCBI 2007»
14 years 9 months ago
Measuring similarities between gene expression profiles through new data transformations
Background: Clustering methods are widely used on gene expression data to categorize genes with similar expression profiles. Finding an appropriate (dis)similarity measure is crit...
Kyungpil Kim, Shibo Zhang, Keni Jiang, Li Cai, In-...
BMCBI
2007
157views more  BMCBI 2007»
14 years 9 months ago
Improving gene set analysis of microarray data by SAM-GS
Background: Gene-set analysis evaluates the expression of biological pathways, or a priori defined gene sets, rather than that of individual genes, in association with a binary ph...
Irina Dinu, John D. Potter, Thomas Mueller, Qi Liu...
BMCBI
2008
126views more  BMCBI 2008»
14 years 9 months ago
Relating gene expression data on two-component systems to functional annotations in Escherichia coli
Background: Obtaining physiological insights from microarray experiments requires computational techniques that relate gene expression data to functional information. Traditionall...
Anne M. Denton, Jianfei Wu, Megan K. Townsend, Pre...
ACAL
2007
Springer
15 years 3 months ago
An Integrated QAP-Based Approach to Visualize Patterns of Gene Expression Similarity
Abstract. This paper illustrates how the Quadratic Assignment Problem (QAP) is used as a mathematical model that helps to produce a visualization of microarray data, based on the r...
Mario Inostroza-Ponta, Alexandre Mendes, Regina Be...
BMCBI
2007
164views more  BMCBI 2007»
14 years 9 months ago
Comparison of probabilistic Boolean network and dynamic Bayesian network approaches for inferring gene regulatory networks
Background: The regulation of gene expression is achieved through gene regulatory networks (GRNs) in which collections of genes interact with one another and other substances in a...
Peng Li, Chaoyang Zhang, Edward J. Perkins, Ping G...