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BMCBI
2005
113views more  BMCBI 2005»
14 years 9 months ago
Pathway level analysis of gene expression using singular value decomposition
Background: A promising direction in the analysis of gene expression focuses on the changes in expression of specific predefined sets of genes that are known in advance to be rela...
John K. Tomfohr, Jun Lu, Thomas B. Kepler
BMCBI
2005
137views more  BMCBI 2005»
14 years 9 months ago
ArrayQuest: a web resource for the analysis of DNA microarray data
Background: Numerous microarray analysis programs have been created through the efforts of Open Source software development projects. Providing browser-based interfaces that allow...
Gary L. Argraves, Saurin D. Jani, Jeremy L. Barth,...
CMIG
2010
110views more  CMIG 2010»
14 years 4 months ago
Unsupervised SVM-based gridding for DNA microarray images
This paper presents a novel method for unsupervised DNA microarray gridding based on Support Vector Machines (SVMs). Each spot is a small region on the microarray surface where cha...
Dimitris G. Bariamis, Dimitris Maroulis, Dimitrios...
BMCBI
2006
171views more  BMCBI 2006»
14 years 9 months ago
The effect of oligonucleotide microarray data pre-processing on the analysis of patient-cohort studies
Background: Intensity values measured by Affymetrix microarrays have to be both normalized, to be able to compare different microarrays by removing non-biological variation, and s...
Roel G. W. Verhaak, Frank J. T. Staal, Peter J. M....
BMCBI
2010
156views more  BMCBI 2010»
14 years 9 months ago
Evaluation of statistical methods for normalization and differential expression in mRNA-Seq experiments
Background: High-throughput sequencing technologies, such as the Illumina Genome Analyzer, are powerful new tools for investigating a wide range of biological and medical question...
James H. Bullard, Elizabeth Purdom, Kasper D. Hans...