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ICGA
1997
122views Optimization» more  ICGA 1997»
13 years 7 months ago
A Comparison of Global and Local Search Methods in Drug Docking
Molecular docking software makes computational predictions of the interaction of molecules. This can be useful, for example, in evaluating the binding of candidate drug molecules ...
Christopher D. Rosin, R. Scott Halliday, William E...
BMCBI
2007
141views more  BMCBI 2007»
13 years 6 months ago
Reconstruction of human protein interolog network using evolutionary conserved network
Background: The recent increase in the use of high-throughput two-hybrid analysis has generated large quantities of data on protein interactions. Specifically, the availability of...
Tao-Wei Huang, Chung-Yen Lin, Cheng-Yan Kao
BMCBI
2007
114views more  BMCBI 2007»
13 years 6 months ago
Probabilistic prediction and ranking of human protein-protein interactions
Background: Although the prediction of protein-protein interactions has been extensively investigated for yeast, few such datasets exist for the far larger proteome in human. Furt...
Michelle S. Scott, Geoffrey J. Barton
ESEM
2007
ACM
13 years 10 months ago
Comparison of Outlier Detection Methods in Fault-proneness Models
In this paper, we experimentally evaluated the effect of outlier detection methods to improve the prediction performance of fault-proneness models. Detected outliers were removed ...
Shinsuke Matsumoto, Yasutaka Kamei, Akito Monden, ...
BMCBI
2005
121views more  BMCBI 2005»
13 years 6 months ago
Automated methods of predicting the function of biological sequences using GO and BLAST
Background: With the exponential increase in genomic sequence data there is a need to develop automated approaches to deducing the biological functions of novel sequences with hig...
Craig E. Jones, Ute Baumann, Alfred L. Brown