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BMCBI
2010
135views more  BMCBI 2010»
13 years 6 months ago
Delineation of amplification, hybridization and location effects in microarray data yields better-quality normalization
Background: Oligonucleotide arrays have become one of the most widely used high-throughput tools in biology. Due to their sensitivity to experimental conditions, normalization is ...
Marc Hulsman, Anouk Mentink, Eugene P. van Someren...
BMCBI
2007
105views more  BMCBI 2007»
13 years 6 months ago
Text-derived concept profiles support assessment of DNA microarray data for acute myeloid leukemia and for androgen receptor sti
Background: High-throughput experiments, such as with DNA microarrays, typically result in hundreds of genes potentially relevant to the process under study, rendering the interpr...
Rob Jelier, Guido Jenster, Lambert C. J. Dorssers,...
BMCBI
2008
135views more  BMCBI 2008»
13 years 6 months ago
Using Generalized Procrustes Analysis (GPA) for normalization of cDNA microarray data
Background: Normalization is essential in dual-labelled microarray data analysis to remove nonbiological variations and systematic biases. Many normalization methods have been use...
Huiling Xiong, Dapeng Zhang, Christopher J. Martyn...
BMCBI
2005
101views more  BMCBI 2005»
13 years 6 months ago
MASQOT: a method for cDNA microarray spot quality control
Background: cDNA microarray technology has emerged as a major player in the parallel detection of biomolecules, but still suffers from fundamental technical problems. Identifying ...
Max Bylesjö, Daniel Eriksson, Andreas Sjö...
BMCBI
2008
117views more  BMCBI 2008»
13 years 6 months ago
New resampling method for evaluating stability of clusters
Background: Hierarchical clustering is a widely applied tool in the analysis of microarray gene expression data. The assessment of cluster stability is a major challenge in cluste...
Irina Gana Dresen, Tanja Boes, Johannes Hüsin...