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BMCBI
2010
14 years 9 months ago
2010
Background: Gene clustering for annotating gene functions is one of the fundamental issues in bioinformatics. The best clustering solution is often regularized by multiple constra...
BMCBI
2010
14 years 9 months ago
2010
Background: The selection of genes that discriminate disease classes from microarray data is widely used for the identification of diagnostic biomarkers. Although various gene sel...
BMCBI
2010
14 years 9 months ago
2010
Background: Transcriptional regulatory network inference (TRNI) from large compendia of DNA microarrays has become a fundamental approach for discovering transcription factor (TF)...
BMCBI
2010
14 years 9 months ago
2010
Background: Mass spectrometry (MS) is an essential analytical tool in proteomics. Many existing algorithms for peptide detection are based on isotope template matching and usually...
BMCBI
2007
14 years 9 months ago
2007
Background: Correct temporal and spatial gene expression during metazoan development relies on combinatorial interactions between different transcription factors. As a consequence...