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BMCBI
2007
142views more  BMCBI 2007»
14 years 9 months ago
Improving model construction of profile HMMs for remote homology detection through structural alignment
Background: Remote homology detection is a challenging problem in Bioinformatics. Arguably, profile Hidden Markov Models (pHMMs) are one of the most successful approaches in addre...
Juliana S. Bernardes, Alberto M. R. Dávila,...
BMCBI
2007
97views more  BMCBI 2007»
14 years 9 months ago
SIRAC: Supervised Identification of Regions of Aberration in aCGH datasets
Background: Array comparative genome hybridization (aCGH) provides information about genomic aberrations. Alterations in the DNA copy number may cause the cell to malfunction, lea...
Carmen Lai, Hugo M. Horlings, Marc J. van de Vijve...
BMCBI
2008
130views more  BMCBI 2008»
14 years 9 months ago
FAF-Drugs2: Free ADME/tox filtering tool to assist drug discovery and chemical biology projects
Background: Drug discovery and chemical biology are exceedingly complex and demanding enterprises. In recent years there are been increasing awareness about the importance of pred...
David Lagorce, Olivier Sperandio, Hervé Gal...
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BMCBI
2008
114views more  BMCBI 2008»
14 years 9 months ago
Testing the Coulomb/Accessible Surface Area solvent model for protein stability, ligand binding, and protein design
Background: Protein structure prediction and computational protein design require efficient yet sufficiently accurate descriptions of aqueous solvent. We continue to evaluate the ...
Marcel Schmidt am Busch, Anne Lopes, Najette Amara...
CN
2008
117views more  CN 2008»
14 years 9 months ago
Packet-switched network selection with the highest QoS in 4G networks
The evolution of telecommunications during the last decades has been enormous and as a result, nowadays, people find themselves before the challenge of 4G networks. Due to the fac...
Dimitris E. Charilas, Ourania I. Markaki, Dimitris...