Background: Missing values frequently pose problems in gene expression microarray experiments as they can hinder downstream analysis of the datasets. While several missing value i...
Johannes Tuikkala, Laura Elo, Olli Nevalainen, Ter...
We propose an unsupervised methodology using independent component analysis (ICA) to cluster genes from DNA microarray data. Based on an ICA mixture model of genomic expression pa...
In microarray gene expression data, clusters may hide in subspaces. Traditional clustering algorithms that make use of similarity measurements in the full input space may fail to ...
Kevin Y. Yip, David W. Cheung, Michael K. Ng, Kei-...
In this paper, a new method for evaluating the quality of clustering of genes is proposed based on mutual information criterion. Instead of using the conventional histogram-based ...
Background The use of clustering methods for the discovery of cancer subtypes has drawn a great deal of attention in the scientific community. While bioinformaticians have propose...