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» Evaluation of clustering algorithms for gene expression data
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BMCBI
2011
14 years 4 months ago
A novel approach to the clustering of microarray data via nonparametric density estimation
Background: Cluster analysis is a crucial tool in several biological and medical studies dealing with microarray data. Such studies pose challenging statistical problems due to di...
Riccardo De Bin, Davide Risso
BMCBI
2008
102views more  BMCBI 2008»
14 years 9 months ago
Response projected clustering for direct association with physiological and clinical response data
Background: Microarray gene expression data are often analyzed together with corresponding physiological response and clinical metadata of biological subjects, e.g. patients'...
Sung-Gon Yi, Taesung Park, Jae K. Lee
PSB
2003
14 years 10 months ago
Decomposing Gene Expression into Cellular Processes
We propose a probabilistic model for cellular processes, and an algorithm for discovering them from gene expression data. A process is associated with a set of genes that particip...
Eran Segal, Alexis Battle, Daphne Koller
BMCBI
2010
115views more  BMCBI 2010»
14 years 9 months ago
Multiconstrained gene clustering based on generalized projections
Background: Gene clustering for annotating gene functions is one of the fundamental issues in bioinformatics. The best clustering solution is often regularized by multiple constra...
Jia Zeng, Shanfeng Zhu, Alan Wee-Chung Liew, Hong ...
BMCBI
2007
207views more  BMCBI 2007»
14 years 9 months ago
Discovering biomarkers from gene expression data for predicting cancer subgroups using neural networks and relational fuzzy clus
Background: The four heterogeneous childhood cancers, neuroblastoma, non-Hodgkin lymphoma, rhabdomyosarcoma, and Ewing sarcoma present a similar histology of small round blue cell...
Nikhil R. Pal, Kripamoy Aguan, Animesh Sharma, Shu...