40 search results - page 4 / 8 » Evaluation of statistical methods for normalization and diff... |
BMCBI
2006
13 years 6 months ago
2006
Background: Recently several statistical methods have been proposed to identify genes with differential expression between two conditions. However, very few studies consider the p...
BMCBI
2004
13 years 6 months ago
2004
Background: Microarray data must be normalized because they suffer from multiple biases. We have identified a source of spatial experimental variability that significantly affects...
BMCBI
2005
13 years 6 months ago
2005
Background: Normalization is a basic step in microarray data analysis. A proper normalization procedure ensures that the intensity ratios provide meaningful measures of relative e...
BMCBI
2008
13 years 6 months ago
2008
Background: Choosing the appropriate sample size is an important step in the design of a microarray experiment, and recently methods have been proposed that estimate sample sizes ...
BMCBI
2004
13 years 6 months ago
2004
Background: A key step in the analysis of microarray expression profiling data is the identification of genes that display statistically significant changes in expression signals ...