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» Evolution of Biological Complexity
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BMCBI
2007
124views more  BMCBI 2007»
15 years 4 months ago
A high-accuracy consensus map of yeast protein complexes reveals modular nature of gene essentiality
Background: Identifying all protein complexes in an organism is a major goal of systems biology. In the past 18 months, the results of two genome-scale tandem affinity purificatio...
G. Traver Hart, Insuk Lee, Edward M. Marcotte
BMCBI
2010
142views more  BMCBI 2010»
15 years 4 months ago
Discover Protein Complexes in Protein-Protein Interaction Networks Using Parametric Local Modularity
Background: Recent advances in proteomic technologies have enabled us to create detailed protein-protein interaction maps in multiple species and in both normal and diseased cells...
Jongkwang Kim, Kai Tan
BMCBI
2008
131views more  BMCBI 2008»
15 years 4 months ago
Modifying the DPClus algorithm for identifying protein complexes based on new topological structures
Background: Identification of protein complexes is crucial for understanding principles of cellular organization and functions. As the size of protein-protein interaction set incr...
Min Li, Jianer Chen, Jianxin Wang, Bin Hu, Gang Ch...
JBCB
2008
71views more  JBCB 2008»
15 years 3 months ago
Using Indirect protein-protein Interactions for protein Complex Prediction
Protein complexes are fundamental for understanding principles of cellular organizations. Accurate and fast protein complex prediction from the PPI networks of increasing sizes ca...
Hon Nian Chua, Kang Ning, Wing-Kin Sung, Hon Wai L...
144
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BIOCOMP
2008
15 years 5 months ago
Bioinformatics Tools: Searching for Markers in DNA/RNA Sequences
Research in bioinformatics and computational biology relies heavily on algorithms that facilitate the understanding of biological processes through the application of statistical ...
Kuha Mahalingam, Omar Bagasra