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» Evolution of Biological Complexity
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BMCBI
2004
196views more  BMCBI 2004»
15 years 3 months ago
MUSCLE: a multiple sequence alignment method with reduced time and space complexity
Background: In a previous paper, we introduced MUSCLE, a new program for creating multiple alignments of protein sequences, giving a brief summary of the algorithm and showing MUS...
Robert C. Edgar
150
Voted
RECOMB
2007
Springer
16 years 4 months ago
Association Mapping of Complex Diseases with Ancestral Recombination Graphs: Models and Efficient Algorithms
Association, or LD (linkage disequilibrium), mapping is an intensely-studied approach to gene mapping (genome-wide or in candidate regions) that is widely hoped to be able to effic...
Yufeng Wu
136
Voted
RECOMB
1997
Springer
15 years 8 months ago
On the complexity and approximation of syntenic distance
The paper studies the computational complexity and approximation algorithms for a new evolutionary distance between multi-chromosomal genomes introduced recently by Ferretti, Nade...
Bhaskar DasGupta, Tao Jiang, Sampath Kannan, Ming ...
BMCBI
2010
102views more  BMCBI 2010»
15 years 4 months ago
SAMPLEX: Automatic mapping of perturbed and unperturbed regions of proteins and complexes
Background: The activity of proteins within the cell is characterized by their motions, flexibility, interactions or even the particularly intriguing case of partially unfolded st...
Mickaël Krzeminski, Karine Loth, Rolf Boelens...
106
Voted
CDC
2008
IEEE
107views Control Systems» more  CDC 2008»
15 years 10 months ago
Resource pooling for optimal evacuation of a large building
— This paper is concerned with modeling, analysis and optimization/control of occupancy evolution in a large building. The main concern is efficient evacuation of a building in ...
Kun Deng, Wei Chen, Prashant G. Mehta, Sean P. Mey...