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» Evolution of Biological Complexity
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GIS
2004
ACM
16 years 5 months ago
Object-relational management of complex geographical objects
Modern database applications including computer-aided design, multimedia information systems, medical imaging, molecular biology, or geographical information systems impose new re...
Hans-Peter Kriegel, Peter Kunath, Martin Pfeifle, ...
CCIA
2007
Springer
15 years 10 months ago
Mendelian error detection in complex pedigrees using weighted constraint satisfaction techniques
With the arrival of high throughput genotyping techniques, the detection of likely genotyping errors is becoming an increasingly important problem. In this paper we are interested...
Martí Sánchez, Simon de Givry, Thoma...
RECOMB
2005
Springer
16 years 4 months ago
Very Low Power to Detect Asymmetric Divergence of Duplicated Genes
Abstract. Asymmetric functional divergence of paralogues is a key aspect of the traditional model of evolution following duplication. If one gene continues to perform the ancestral...
Cathal Seoighe, Konrad Scheffler
CORR
2008
Springer
86views Education» more  CORR 2008»
15 years 4 months ago
Dynamic System Adaptation by Constraint Orchestration
Abstract. For Paradigm models, evolution is just-in-time specified coordination conducted by a special reusable component McPal. Evolution can be treated consistently and on-the-fl...
Luuk Groenewegen, Erik P. de Vink
BMCBI
2007
227views more  BMCBI 2007»
15 years 4 months ago
Growing functional modules from a seed protein via integration of protein interaction and gene expression data
Background: Nowadays modern biology aims at unravelling the strands of complex biological structures such as the protein-protein interaction (PPI) networks. A key concept in the o...
Ioannis A. Maraziotis, Konstantina Dimitrakopoulou...