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» Evolution of Biological Complexity
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BMCBI
2011
14 years 11 months ago
Logical Development of the Cell Ontology
Background: The Cell Ontology (CL) is an ontology for the representation of in vivo cell types. As biological ontologies such as the CL grow in complexity, they become increasingl...
Terrence F. Meehan, Anna Maria Masci, Amina Abdull...
BMCBI
2011
14 years 8 months ago
Assessing the functional coherence of modules found in multiple-evidence networks from Arabidopsis
Background: Combining multiple evidence-types from different information sources has the potential to reveal new relationships in biological systems. The integrated information ca...
Artem Lysenko, Michael Defoin-Platel, Keywan Hassa...
RECOMB
2008
Springer
16 years 4 months ago
Duplication Mechanism and Disruptions in Flanking Regions Influence the Fate of Mammalian Gene Duplicates
Here we identify duplicated genes in five mammalian genomes and classify these duplicates based on the mechanisms by which they were generated. Retrotransposition accounts for at l...
Paul Ryvkin, Jin Jun, Edward Hemphill, Craig Nelso...
RECOMB
2008
Springer
16 years 4 months ago
Internal Validation of Ancestral Gene Order Reconstruction in Angiosperm Phylogeny
Abstract. Whole genome doubling (WGD), a frequent occurrence during the evolution of the angiopsperms, complicates ancestral gene order reconstruction due to the multiplicity of so...
David Sankoff, Chunfang Zheng, P. Kerr Wall, Claud...
RECOMB
2007
Springer
16 years 4 months ago
Rearrangements in Genomes with Centromeres Part I: Translocations
A centromere is a special region in the chromosome that plays a vital role during cell division. Every new chromosome created by a genome rearrangement event must have a centromere...
Michal Ozery-Flato, Ron Shamir