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» Evolution of Biological Complexity
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BMCBI
2008
166views more  BMCBI 2008»
15 years 4 months ago
Learning transcriptional regulatory networks from high throughput gene expression data using continuous three-way mutual informa
Background: Probability based statistical learning methods such as mutual information and Bayesian networks have emerged as a major category of tools for reverse engineering mecha...
Weijun Luo, Kurt D. Hankenson, Peter J. Woolf
CEC
2003
IEEE
15 years 8 months ago
Dynamics of gene expression in an artificial genome
Abstract- Complex systems techniques provide a powerful tool to study the emergent properties of networks of interacting genes. In this study we extract models of genetic regulator...
Kai Willadsen, Janet Wiles
IJIT
2004
15 years 6 months ago
Computing Entropy for Ortholog Detection
Abstract-- Biological sequences from different species are called orthologs if they evolved from a sequence of a common ancestor species and they have the same biological function....
Hsing-Kuo Pao, John Case
BMCBI
2008
106views more  BMCBI 2008»
15 years 4 months ago
Identification of hot-spot residues in protein-protein interactions by computational docking
Background: The study of protein-protein interactions is becoming increasingly important for biotechnological and therapeutic reasons. We can define two major areas therein: the s...
Solène Grosdidier, Juan Fernández-Re...
BIRTHDAY
2009
Springer
15 years 11 months ago
Foundations of Temporal Conceptual Data Models
Abstract. This chapter considers the different temporal constructs appeared in the literature of temporal conceptual models (timestamping and evolution constraints), and it provid...
Alessandro Artale, Enrico Franconi