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» Evolution of Biological Complexity
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138
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ECCB
2002
IEEE
15 years 10 months ago
Stochastic roadmap simulation for the study of ligand-protein interactions
The dynamics of ligand-protein interactions are necessary to understand for the design of novel therapeutic agents. In this paper, we establish the use of Stochastic Roadmap Simul...
Mehmet Serkan Apaydin, Carlos Guestrin, Chris Varm...
132
Voted
CSB
2004
IEEE
112views Bioinformatics» more  CSB 2004»
15 years 8 months ago
Reasoning about Molecular Similarity and Properties
Ascertaining the similarity amongst molecules is a fundamental problem in biology and drug discovery. Since similar molecules tend to have similar biological properties, the notio...
Rahul Singh
BIOADIT
2006
Springer
15 years 8 months ago
Robot Control: From Silicon Circuitry to Cells
Life-like adaptive behaviour is so far an illusive goal in robot control. A capability to act successfully in a complex, ambiguous, and harsh environment would vastly increase the ...
Soichiro Tsuda, Klaus-Peter Zauner, Yukio-Pegio Gu...
BMCBI
2010
150views more  BMCBI 2010»
15 years 5 months ago
Systematic calibration of a cell signaling network model
Background: Mathematical modeling is being applied to increasingly complex biological systems and datasets; however, the process of analyzing and calibrating against experimental ...
Kyoung Ae Kim, Sabrina L. Spencer, John G. Albeck,...
BMCBI
2007
135views more  BMCBI 2007»
15 years 5 months ago
Detecting multivariate differentially expressed genes
Background: Gene expression is governed by complex networks, and differences in expression patterns between distinct biological conditions may therefore be complex and multivariat...
Roland Nilsson, José M. Peña, Johan ...