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BMEI
2008
IEEE
15 years 11 months ago
A New Approach for Tree Alignment Based on Local Re-Optimization
Multiple sequence alignment is the most fundamental task in bioinformatics and computational biology. In this paper, we present a new algorithm to conduct multiple sequences align...
Feng Yue, Jijun Tang
CIBCB
2008
IEEE
15 years 11 months ago
Discovering novel cancer therapies: A computational modeling and search approach
— Solid tumors must recruit new blood vessels for growth and maintenance. Discovering drugs that block this tumor-induced development of new blood vessels (angiogenesis) is an im...
Arthur W. Mahoney, Brian G. Smith, Nicholas S. Fla...
ICDM
2007
IEEE
175views Data Mining» more  ICDM 2007»
15 years 10 months ago
gApprox: Mining Frequent Approximate Patterns from a Massive Network
Recently, there arise a large number of graphs with massive sizes and complex structures in many new applications, such as biological networks, social networks, and the Web, deman...
Chen Chen, Xifeng Yan, Feida Zhu, Jiawei Han
DEXA
2007
Springer
150views Database» more  DEXA 2007»
15 years 10 months ago
Sequence Alignment as a Database Technology Challenge
Abstract. Sequence alignment is an important task for molecular biologists. Because alignment basically deals with approximate string matching on large biological sequence collecti...
Hans Philippi
GECCO
2007
Springer
189views Optimization» more  GECCO 2007»
15 years 10 months ago
A more bio-plausible approach to the evolutionary inference of finite state machines
With resemblance of finite-state machines to some biological mechanisms in cells and numerous applications of finite automata in different fields, this paper uses analogies an...
Hooman Shayani, Peter J. Bentley