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» Evolution of Biological Complexity
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116
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BMCBI
2006
99views more  BMCBI 2006»
15 years 22 days ago
A proposed metric for assessing the measurement quality of individual microarrays
Background: High-density microarray technology is increasingly applied to study gene expression levels on a large scale. Microarray experiments rely on several critical steps that...
Kyoungmi Kim, Grier P. Page, T. Mark Beasley, Step...
112
Voted
BMCBI
2006
180views more  BMCBI 2006»
15 years 22 days ago
The Gaggle: An open-source software system for integrating bioinformatics software and data sources
Background: Systems biologists work with many kinds of data, from many different sources, using a variety of software tools. Each of these tools typically excels at one type of an...
Paul T. Shannon, David J. Reiss, Richard Bonneau, ...
95
Voted
BMCBI
2006
122views more  BMCBI 2006»
15 years 22 days ago
BioMoby extensions to the Taverna workflow management and enactment software
Background: As biology becomes an increasingly computational science, it is critical that we develop software tools that support not only bioinformaticians, but also bench biologi...
Edward A. Kawas, Martin Senger, Mark D. Wilkinson
101
Voted
BMCBI
2006
107views more  BMCBI 2006»
15 years 22 days ago
CROPPER: a metagene creator resource for cross-platform and cross-species compendium studies
Background: Current genomic research methods provide researchers with enormous amounts of data. Combining data from different high-throughput research technologies commonly availa...
Jussi Paananen, Markus Storvik, Garry Wong
116
Voted
BMCBI
2006
205views more  BMCBI 2006»
15 years 22 days ago
Application of Petri net based analysis techniques to signal transduction pathways
Background: Signal transduction pathways are usually modelled using classical quantitative methods, which are based on ordinary differential equations (ODEs). However, some diffic...
Andrea Sackmann, Monika Heiner, Ina Koch