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» Evolution of Biological Complexity
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101
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BMCBI
2006
133views more  BMCBI 2006»
15 years 22 days ago
An integrated approach to the prediction of domain-domain interactions
Background: The development of high-throughput technologies has produced several large scale protein interaction data sets for multiple species, and significant efforts have been ...
Hyunju Lee, Minghua Deng, Fengzhu Sun, Ting Chen
91
Voted
BMCBI
2006
133views more  BMCBI 2006»
15 years 22 days ago
Web-based analysis of the mouse transcriptome using Genevestigator
Background: Gene function analysis often requires a complex and laborious sequence of laboratory and computer-based experiments. Choosing an effective experimental design generall...
Oliver Laule, Matthias Hirsch-Hoffmann, Tomas Hruz...
107
Voted
BMCBI
2006
116views more  BMCBI 2006»
15 years 22 days ago
Optimized mixed Markov models for motif identification
Background: Identifying functional elements, such as transcriptional factor binding sites, is a fundamental step in reconstructing gene regulatory networks and remains a challengi...
Weichun Huang, David M. Umbach, Uwe Ohler, Leping ...
119
Voted
BMCBI
2007
200views more  BMCBI 2007»
15 years 21 days ago
BNDB - The Biochemical Network Database
Background: Technological advances in high-throughput techniques and efficient data acquisition methods have resulted in a massive amount of life science data. The data is stored ...
Jan Küntzer, Christina Backes, Torsten Blum, ...
100
Voted
BMCBI
2007
96views more  BMCBI 2007»
15 years 21 days ago
Features generated for computational splice-site prediction correspond to functional elements
Background: Accurate selection of splice sites during the splicing of precursors to messenger RNA requires both relatively well-characterized signals at the splice sites and auxil...
Rezarta Islamaj Dogan, Lise Getoor, W. John Wilbur...