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» Evolution of Biological Complexity
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126
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GPEM
2007
87views more  GPEM 2007»
15 years 3 months ago
Motility, mixing, and multicellularity
Abstract. A fundamental issue in evolutionary biology is the transition from unicellular to multicellular organisms, and the cellular differentiation that accompanies the increase...
Cristian A. Solari, John O. Kessler, Raymond E. Go...
150
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ALIFE
2005
15 years 3 months ago
State Aggregation and Population Dynamics in Linear Systems
We consider complex systems that are composed of many interacting elements, evolving under some dynamics. We are interested in characterizing the ways in which these elements may b...
Jonathan E. Rowe, Michael D. Vose, Alden H. Wright
116
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BMCBI
2005
77views more  BMCBI 2005»
15 years 3 months ago
Ontological visualization of protein-protein interactions
Background: Cellular processes require the interaction of many proteins across several cellular compartments. Determining the collective network of such interactions is an importa...
Harold J. Drabkin, Christopher Hollenbeck, David P...
138
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BMCBI
2005
115views more  BMCBI 2005»
15 years 3 months ago
Statistical distributions of optimal global alignment scores of random protein sequences
Background: The inference of homology from statistically significant sequence similarity is a central issue in sequence alignments. So far the statistical distribution function un...
Hongxia Pang, Jiaowei Tang, Su-Shing Chen, Shiheng...
150
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BMCBI
2005
124views more  BMCBI 2005»
15 years 3 months ago
Tools enabling the elucidation of molecular pathways active in human disease: Application to Hepatitis C virus infection
Background: The extraction of biological knowledge from genome-scale data sets requires its analysis in the context of additional biological information. The importance of integra...
David J. Reiss, Iliana Avila-Campillo, Vesteinn Th...