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» Evolution of Biological Complexity
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143
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BMCBI
2005
122views more  BMCBI 2005»
15 years 3 months ago
Computational verification of protein-protein interactions by orthologous co-expression
Background: High-throughput methods identify an overwhelming number of protein-protein interactions. However, the limited accuracy of these methods results in the false identifica...
Itay Tirosh, Naama Barkai
157
Voted
BMCBI
2005
113views more  BMCBI 2005»
15 years 3 months ago
Pathway level analysis of gene expression using singular value decomposition
Background: A promising direction in the analysis of gene expression focuses on the changes in expression of specific predefined sets of genes that are known in advance to be rela...
John K. Tomfohr, Jun Lu, Thomas B. Kepler
139
Voted
BMCBI
2005
142views more  BMCBI 2005»
15 years 3 months ago
High performance workflow implementation for protein surface characterization using grid technology
Background: This study concerns the development of a high performance workflow that, using grid technology, correlates different kinds of Bioinformatics data, starting from the ba...
Ivan Merelli, Giulia Morra, Daniele D'Agostino, An...
162
Voted
JCB
2007
145views more  JCB 2007»
15 years 3 months ago
Confounding Factors in HGT Detection: Statistical Error, Coalescent Effects, and Multiple Solutions
Prokaryotic organisms share genetic material across species boundaries by means of a process known as horizontal gene transfer (HGT). This process has great significance for unde...
Cuong Than, Derek A. Ruths, Hideki Innan, Luay Nak...
172
Voted
BC
2002
193views more  BC 2002»
15 years 3 months ago
Resonant spatiotemporal learning in large random recurrent networks
Taking a global analogy with the structure of perceptual biological systems, we present a system composed of two layers of real-valued sigmoidal neurons. The primary layer receives...
Emmanuel Daucé, Mathias Quoy, Bernard Doyon