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BMCBI
2007
14 years 12 months ago
2007
Background: Transcription factors (TFs) are key regulatory proteins that enhance or repress the transcriptional rate of their target genes by binding to specific promoter regions ...
102
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BMCBI
2007
14 years 12 months ago
2007
Background: A widely-used approach for discovering functional and physical interactions among proteins involves phylogenetic profile comparisons (PPCs). Here, proteins with simila...
105
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BMCBI
2007
14 years 12 months ago
2007
Background: Coalescent simulations have proven very useful in many population genetics studies. In order to arrive to meaningful conclusions, it is important that these simulation...
BMCBI
2007
14 years 12 months ago
2007
Background: The relationship between divergence of amino-acid sequence and divergence of function among homologous proteins is complex. The assumption that homologs share function...
BMCBI
2007
14 years 12 months ago
2007
Background: In Archeae and Bacteria, the repeated elements called CRISPRs for "clustered regularly interspaced short palindromic repeats" are believed to participate in ...