Motivation: Intervention in a gene regulatory network is used to help it avoid undesirable states, such as those associated with a disease. Several types of intervention have been...
Ranadip Pal, Aniruddha Datta, Michael L. Bittner, ...
Background: Most proteins function by interacting with other molecules. Their interaction interfaces are highly conserved throughout evolution to avoid undesirable interactions th...
Sungsam Gong, Changbum Park, Hansol Choi, Junsu Ko...
Background: The availability of interaction databases provides an opportunity for researchers to utilize immense amounts of data exclusively in silico. Recently there has been an ...
: One of the most evident achievements of bioinformatics is the development of methods that transfer biological knowledge from characterised proteins to uncharacterised sequences. ...
Emmanuel D. Levy, Christos A. Ouzounis, Walter R. ...
Background: Coalescent simulations are playing a large role in interpreting large scale intraspecific sequence or polymorphism surveys and for planning and evaluating association ...
Thomas Mailund, Mikkel H. Schierup, Christian N. S...