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BMCBI
2005
94views more  BMCBI 2005»
14 years 11 months ago
Visualization-based discovery and analysis of genomic aberrations in microarray data
Background: Chromosomal copy number changes (aneuploidies) play a key role in cancer progression and molecular evolution. These copy number changes can be studied using microarray...
Chad L. Myers, Xing Chen, Olga G. Troyanskaya
BMCBI
2005
147views more  BMCBI 2005»
14 years 11 months ago
GATA: a graphic alignment tool for comparative sequence analysis
Background: Several problems exist with current methods used to align DNA sequences for comparative sequence analysis. Most dynamic programming algorithms assume that conserved se...
David A. Nix, Michael B. Eisen
JASIS
2007
121views more  JASIS 2007»
14 years 11 months ago
Can citation analysis of Web publications better detect research fronts?
We present evidence that, in some research fields, research published in journals and reported on the Web may collectively represent different evolutionary stages of the field wit...
Dangzhi Zhao, Andreas Strotmann
BMCBI
2005
100views more  BMCBI 2005»
14 years 11 months ago
Evolutionary models for insertions and deletions in a probabilistic modeling framework
Background: Probabilistic models for sequence comparison (such as hidden Markov models and pair hidden Markov models for proteins and mRNAs, or their context-free grammar counterp...
Elena Rivas
BMCBI
2005
97views more  BMCBI 2005»
14 years 11 months ago
Evolutionary distance estimation and fidelity of pair wise sequence alignment
Background: Evolutionary distances are a critical measure in comparative genomics and molecular evolutionary biology. A simulation study was used to examine the effect of alignmen...
Michael S. Rosenberg
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