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» Evolution with Drifting Targets
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75
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BMCBI
2007
97views more  BMCBI 2007»
14 years 9 months ago
In situ analysis of cross-hybridisation on microarrays and the inference of expression correlation
Background: Microarray co-expression signatures are an important tool for studying gene function and relations between genes. In addition to genuine biological co-expression, corr...
Tineke Casneuf, Yves Van de Peer, Wolfgang Huber
BMCBI
2008
105views more  BMCBI 2008»
14 years 9 months ago
Improving the prediction of mRNA extremities in the parasitic protozoan Leishmania
Background: Leishmania and other members of the Trypanosomatidae family diverged early on in eukaryotic evolution and consequently display unique cellular properties. Their appare...
Martin Smith, Mathieu Blanchette, Barbara Papadopo...
74
Voted
BMCBI
2010
128views more  BMCBI 2010»
14 years 9 months ago
Conserved residue clusters at protein-protein interfaces and their use in binding site identification
Background: Biological evolution conserves protein residues that are important for structure and function. Both protein stability and function often require a certain degree of st...
Mainak Guharoy, Pinak Chakrabarti
BMCBI
2006
149views more  BMCBI 2006»
14 years 9 months ago
Curation of viral genomes: challenges, applications and the way forward
Background: Whole genome sequence data is a step towards generating the 'parts list' of life to understand the underlying principles of Biocomplexity. Genome sequencing ...
Urmila Kulkarni-Kale, Shriram Bhosle, G. Sunitha M...
EAAI
2006
189views more  EAAI 2006»
14 years 9 months ago
Evolutionary algorithms for VLSI multi-objective netlist partitioning
The problem of partitioning appears in several areas ranging from VLSI, parallel programming, to molecular biology. The interest in finding an optimal partition especially in VLSI ...
Sadiq M. Sait, Aiman H. El-Maleh, Raslan H. Al-Aba...