69 search results - page 12 / 14 » Evolutionary Approaches to DNA Sequencing with Errors |
96
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ALMOB
2008
15 years 13 days ago
2008
Motivation: Sequence-based methods for phylogenetic reconstruction from (nucleic acid) sequence data are notoriously plagued by two effects: homoplasies and alignment errors. Larg...
BMCBI
2008
15 years 13 days ago
2008
Background: Comparative genomics aims to detect signals of evolutionary conservation as an indicator of functional constraint. Surprisingly, results of the ENCODE project revealed...
129
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BMCBI
2011
14 years 3 months ago
2011
Background: Estimation of allele frequency is of fundamental importance in population genetic analyses and in association mapping. In most studies using next-generation sequencing...
125
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ESWA
2006
15 years 9 days ago
2006
Artificial intelligence (AI) has increasingly gained attention in bioinformatics research and computational molecular biology. With the availability of different types of AI algor...
BMCBI
2008
15 years 13 days ago
2008
Background: The availability of complete genomic sequences for hundreds of organisms promises to make obtaining genome-wide estimates of substitution rates, selective constraints ...