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» Evolutionary Approaches to DNA Sequencing with Errors
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BMCBI
2005
118views more  BMCBI 2005»
15 years 7 days ago
Vestige: Maximum likelihood phylogenetic footprinting
Background: Phylogenetic footprinting is the identification of functional regions of DNA by their evolutionary conservation. This is achieved by comparing orthologous regions from...
Matthew J. Wakefield, Peter Maxwell, Gavin A. Hutt...
BMCBI
2006
132views more  BMCBI 2006»
15 years 11 days ago
Genome-wide DNA polymorphism analyses using VariScan
Background: DNA sequence polymorphisms analysis can provide valuable information on the evolutionary forces shaping nucleotide variation, and provides an insight into the function...
Stephan Hutter, Albert J. Vilella, Julio Rozas
BMCBI
2006
115views more  BMCBI 2006»
15 years 11 days ago
Detecting recombination in evolving nucleotide sequences
Background: Genetic recombination can produce heterogeneous phylogenetic histories within a set of homologous genes. These recombination events can be obscured by subsequent resid...
Cheong Xin Chan, Robert G. Beiko, Mark A. Ragan
GCB
2006
Springer
140views Biometrics» more  GCB 2006»
15 years 4 months ago
PALMA: Perfect Alignments using Large Margin Algorithms
: Despite many years of research on how to properly align sequences in the presence of sequencing errors, alternative splicing and micro-exons, the correct alignment of mRNA sequen...
Gunnar Rätsch, Bettina Hepp, Uta Schulze, Che...
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CSB
2003
IEEE
15 years 5 months ago
Group Testing With DNA Chips: Generating Designs and Decoding Experiments
DNA microarrays are a valuable tool for massively parallel DNA-DNA hybridization experiments. Currently, most applications rely on the existence of sequence-specific oligonucleot...
Alexander Schliep, David C. Torney, Sven Rahmann