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» Evolutionary Approaches to DNA Sequencing with Errors
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BIOINFORMATICS
2010
138views more  BIOINFORMATICS 2010»
15 years 14 days ago
Robust unmixing of tumor states in array comparative genomic hybridization data
Motivation: Tumorigenesis is an evolutionary process by which tumor cells acquire sequences of mutations leading to increased growth, invasiveness, and eventually metastasis. It i...
David Tolliver, Charalampos E. Tsourakakis, Ayshwa...
BMCBI
2008
104views more  BMCBI 2008»
15 years 14 days ago
ReRep: Computational detection of repetitive sequences in genome survey sequences (GSS)
Background: Genome survey sequences (GSS) offer a preliminary global view of a genome since, unlike ESTs, they cover coding as well as non-coding DNA and include repetitive region...
Thomas D. Otto, Leonardo H. F. Gomes, Marcelo Alve...
ICCS
2009
Springer
15 years 7 months ago
A Massively Parallel Architecture for Bioinformatics
Abstract. Today’s general purpose computers lack in meeting the requirements on computing performance for standard applications in bioinformatics like DNA sequence alignment, err...
Gerd Pfeiffer, Stefan Baumgart, Jan Schröder,...
BMCBI
2008
96views more  BMCBI 2008»
15 years 14 days ago
Novel methodology for construction and pruning of quasi-median networks
Background: Visualising the evolutionary history of a set of sequences is a challenge for molecular phylogenetics. One approach is to use undirected graphs, such as median network...
Sarah C. Ayling, Terence A. Brown
CIKM
2008
Springer
15 years 2 months ago
Pairwise statistical significance of local sequence alignment using multiple parameter sets
Background: Accurate estimation of statistical significance of a pairwise alignment is an important problem in sequence comparison. Recently, a comparative study of pairwise stati...
Ankit Agrawal, Xiaoqiu Huang