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» Evolutionary computation: a unified approach
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BMCBI
2007
163views more  BMCBI 2007»
14 years 10 months ago
Strainer: software for analysis of population variation in community genomic datasets
Background: Metagenomic analyses of microbial communities that are comprehensive enough to provide multiple samples of most loci in the genomes of the dominant organism types will...
John M. Eppley, Gene W. Tyson, Wayne M. Getz, Jill...
BMCBI
2010
177views more  BMCBI 2010»
14 years 10 months ago
Clustering of protein families into functional subtypes using Relative Complexity Measure with reduced amino acid alphabets
Background: Phylogenetic analysis can be used to divide a protein family into subfamilies in the absence of experimental information. Most phylogenetic analysis methods utilize mu...
Aydin Albayrak, Hasan H. Otu, Ugur O. Sezerman
GPEM
2008
98views more  GPEM 2008»
14 years 10 months ago
Sporadic model building for efficiency enhancement of the hierarchical BOA
Efficiency enhancement techniques--such as parallelization and hybridization--are among the most important ingredients of practical applications of genetic and evolutionary algori...
Martin Pelikan, Kumara Sastry, David E. Goldberg
BMCBI
2007
144views more  BMCBI 2007»
14 years 9 months ago
Motif kernel generated by genetic programming improves remote homology and fold detection
Background: Protein remote homology detection is a central problem in computational biology. Most recent methods train support vector machines to discriminate between related and ...
Tony Håndstad, Arne J. H. Hestnes, Pål...
BMCBI
2010
108views more  BMCBI 2010»
14 years 7 months ago
BIGSdb: Scalable analysis of bacterial genome variation at the population level
Background: The opportunities for bacterial population genomics that are being realised by the application of parallel nucleotide sequencing require novel bioinformatics platforms...
Keith A. Jolley, Martin C. J. Maiden