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BMCBI
2007
102views more  BMCBI 2007»
15 years 2 months ago
Identification of homologs in insignificant blast hits by exploiting extrinsic gene properties
Background: Homology is a key concept in both evolutionary biology and genomics. Detection of homology is crucial in fields like the functional annotation of protein sequences and...
Jos Boekhorst, Berend Snel
142
Voted
BMCBI
2007
144views more  BMCBI 2007»
15 years 1 months ago
Motif kernel generated by genetic programming improves remote homology and fold detection
Background: Protein remote homology detection is a central problem in computational biology. Most recent methods train support vector machines to discriminate between related and ...
Tony Håndstad, Arne J. H. Hestnes, Pål...
GECCO
2005
Springer
189views Optimization» more  GECCO 2005»
15 years 7 months ago
Molecular programming: evolving genetic programs in a test tube
We present a molecular computing algorithm for evolving DNA-encoded genetic programs in a test tube. The use of synthetic DNA molecules combined with biochemical techniques for va...
Byoung-Tak Zhang, Ha-Young Jang
87
Voted
GECCO
2003
Springer
15 years 7 months ago
Effective Use of Directional Information in Multi-objective Evolutionary Computation
While genetically inspired approaches to multi-objective optimization have many advantages over conventional approaches, they do not explicitly exploit directional/gradient informa...
Martin Brown, Robert E. Smith
113
Voted
EVOW
2001
Springer
15 years 6 months ago
A Constructive Evolutionary Approach to School Timetabling
This work presents a constructive approach to the process of fixing a sequence of meetings between teachers and students in a prefixed period of time, satisfying a set of constrain...
Geraldo Ribeiro Filho, Luiz Antonio Nogueira Loren...