Background: A number of methods that use both protein structural and evolutionary information are available to predict the functional consequences of missense mutations. However, ...
Chris J. Needham, James R. Bradford, Andrew J. Bul...
We have developed a web tool, PupaSuite, for the selection of single nucleotide polymorphisms (SNPs) with potential phenotypic effect, specifically oriented to help in the design ...
The SUPERFAMILY database provides protein domain assignments, at the SCOP ‘superfamily’ level, for the predicted protein sequences in over 400 completed genomes. A superfamily...
Derek Wilson, Martin Madera, Christine Vogel, Cyru...
Many problems require recursively speci ed types ofdata and a collection of tools that operate on those data. Over time, these problems evolve so that the programmer must extend t...
Shriram Krishnamurthi, Matthias Felleisen, Daniel ...
This paper introduces a function that increases the amount of neutrality (inactive code in Genetic Programming) for the Artificial Ant Problem. The objective of this approach is t...