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BMCBI
2006
118views more  BMCBI 2006»
15 years 3 months ago
Predicting the effect of missense mutations on protein function: analysis with Bayesian networks
Background: A number of methods that use both protein structural and evolutionary information are available to predict the functional consequences of missense mutations. However, ...
Chris J. Needham, James R. Bradford, Andrew J. Bul...
NAR
2006
88views more  NAR 2006»
15 years 2 months ago
PupaSuite: finding functional single nucleotide polymorphisms for large-scale genotyping purposes
We have developed a web tool, PupaSuite, for the selection of single nucleotide polymorphisms (SNPs) with potential phenotypic effect, specifically oriented to help in the design ...
Lucía Conde, Juan M. Vaquerizas, Hern&aacut...
NAR
2007
90views more  NAR 2007»
15 years 2 months ago
The SUPERFAMILY database in 2007: families and functions
The SUPERFAMILY database provides protein domain assignments, at the SCOP ‘superfamily’ level, for the predicted protein sequences in over 400 completed genomes. A superfamily...
Derek Wilson, Martin Madera, Christine Vogel, Cyru...
ECOOP
1998
Springer
15 years 7 months ago
Synthesizing Object-Oriented and Functional Design to Promote Re-Use
Many problems require recursively speci ed types ofdata and a collection of tools that operate on those data. Over time, these problems evolve so that the programmer must extend t...
Shriram Krishnamurthi, Matthias Felleisen, Daniel ...
GECCO
2007
Springer
158views Optimization» more  GECCO 2007»
15 years 6 months ago
A GP neutral function for the artificial ANT problem
This paper introduces a function that increases the amount of neutrality (inactive code in Genetic Programming) for the Artificial Ant Problem. The objective of this approach is t...
Esteban Ricalde, Katya Rodríguez-Váz...