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BMCBI
2007
107views more  BMCBI 2007»
15 years 4 months ago
A general and efficient method for estimating continuous IBD functions for use in genome scans for QTL
Background: Identity by descent (IBD) matrix estimation is a central component in mapping of Quantitative Trait Loci (QTL) using variance component models. A large number of algor...
Francois Besnier, Örjan Carlborg
BMCBI
2008
102views more  BMCBI 2008»
15 years 4 months ago
Improving protein function prediction methods with integrated literature data
Background: Determining the function of uncharacterized proteins is a major challenge in the post-genomic era due to the problem's complexity and scale. Identifying a protein...
Aaron Gabow, Sonia M. Leach, William A. Baumgartne...
BMCBI
2005
121views more  BMCBI 2005»
15 years 4 months ago
Automated methods of predicting the function of biological sequences using GO and BLAST
Background: With the exponential increase in genomic sequence data there is a need to develop automated approaches to deducing the biological functions of novel sequences with hig...
Craig E. Jones, Ute Baumann, Alfred L. Brown
ECCC
2008
93views more  ECCC 2008»
15 years 3 months ago
A Note on the Distance to Monotonicity of Boolean Functions
Given a function f : {0, 1}n {0, 1}, let M (f) denote the smallest distance between f and a monotone function on {0, 1}n . Let M (f) denote the fraction of hypercube edges where f...
Arnab Bhattacharyya
CSB
2005
IEEE
189views Bioinformatics» more  CSB 2005»
15 years 9 months ago
Learning Yeast Gene Functions from Heterogeneous Sources of Data Using Hybrid Weighted Bayesian Networks
We developed a machine learning system for determining gene functions from heterogeneous sources of data sets using a Weighted Naive Bayesian Network (WNB). The knowledge of gene ...
Xutao Deng, Huimin Geng, Hesham H. Ali