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ATAL
2008
Springer
15 years 6 months ago
Adaptive Kanerva-based function approximation for multi-agent systems
In this paper, we show how adaptive prototype optimization can be used to improve the performance of function approximation based on Kanerva Coding when solving largescale instanc...
Cheng Wu, Waleed Meleis
BIOINFORMATICS
2007
151views more  BIOINFORMATICS 2007»
15 years 4 months ago
A new protein-protein docking scoring function based on interface residue properties
Motivation: Protein–protein complexes are known to play key roles in many cellular processes. However, they are often not accessible to experimental study because of their low s...
Julie Bernauer, Jérôme Azé, Jo...
BMCBI
2010
105views more  BMCBI 2010»
15 years 4 months ago
A knowledge-guided strategy for improving the accuracy of scoring functions in binding affinity prediction
Background: Current scoring functions are not very successful in protein-ligand binding affinity prediction albeit their popularity in structure-based drug designs. Here, we propo...
Tiejun Cheng, Zhihai Liu, Renxiao Wang
125
Voted
BMCBI
2006
109views more  BMCBI 2006»
15 years 4 months ago
A computational approach to discovering the functions of bacterial phytochromes by analysis of homolog distributions
Background: Phytochromes are photoreceptors, discovered in plants, that control a wide variety of developmental processes. They have also been found in bacteria and fungi, but for...
Tilman Lamparter
181
Voted
NAR
2008
174views more  NAR 2008»
15 years 2 months ago
miRGator: an integrated system for functional annotation of microRNAs
MicroRNAs (miRNAs) constitute an important class of regulators that are involved in various cellular and disease processes. However, the functional significance of each miRNA is m...
Seungyoon Nam, Bumjin Kim, Seokmin Shin, Sanghyuk ...