Sciweavers

4167 search results - page 324 / 834
» Evolutionary functional testing
Sort
View
BMCBI
2007
183views more  BMCBI 2007»
15 years 4 months ago
Considerations in the identification of functional RNA structural elements in genomic alignments
Background: Accurate identification of novel, functional noncoding (nc) RNA features in genome sequence has proven more difficult than for exons. Current algorithms identify and s...
Tomas Babak, Benjamin J. Blencowe, Timothy R. Hugh...
BMCBI
2007
157views more  BMCBI 2007»
15 years 4 months ago
Constructing gene co-expression networks and predicting functions of unknown genes by random matrix theory
Background: Large-scale sequencing of entire genomes has ushered in a new age in biology. One of the next grand challenges is to dissect the cellular networks consisting of many i...
Feng Luo, Yunfeng Yang, Jianxin Zhong, Haichun Gao...
BMCBI
2006
143views more  BMCBI 2006»
15 years 4 months ago
Discovering functional gene expression patterns in the metabolic network of Escherichia coli with wavelets transforms
Background: Microarray technology produces gene expression data on a genomic scale for an endless variety of organisms and conditions. However, this vast amount of information nee...
Rainer König, Gunnar Schramm, Marcus Oswald, ...
BMCBI
2005
122views more  BMCBI 2005»
15 years 4 months ago
FACT - a framework for the functional interpretation of high-throughput experiments
Background: Interpreting the results of high-throughput experiments, such as those obtained from DNA-microarrays, is an often time-consuming task due to the high number of data-po...
Felix Kokocinski, Nicolas Delhomme, Gunnar Wrobel,...
JBCB
2010
123views more  JBCB 2010»
15 years 2 months ago
Characterizing the Space of interatomic Distance Distribution Functions Consistent with Solution Scattering Data
: Scattering of neutrons and x-rays from molecules in solution offers alternative approaches to the studying of a wide range of macromolecular structures in their solution state w...
Paritosh A. Kavathekar, Bruce A. Craig, Alan M. Fr...