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BIOINFORMATICS
2010
138views more  BIOINFORMATICS 2010»
15 years 4 months ago
Robust unmixing of tumor states in array comparative genomic hybridization data
Motivation: Tumorigenesis is an evolutionary process by which tumor cells acquire sequences of mutations leading to increased growth, invasiveness, and eventually metastasis. It i...
David Tolliver, Charalampos E. Tsourakakis, Ayshwa...
BMCBI
2007
163views more  BMCBI 2007»
15 years 4 months ago
Strainer: software for analysis of population variation in community genomic datasets
Background: Metagenomic analyses of microbial communities that are comprehensive enough to provide multiple samples of most loci in the genomes of the dominant organism types will...
John M. Eppley, Gene W. Tyson, Wayne M. Getz, Jill...
BMCBI
2007
153views more  BMCBI 2007»
15 years 4 months ago
An exploration of alternative visualisations of the basic helix-loop-helix protein interaction network
Background: Alternative representations of biochemical networks emphasise different aspects of the data and contribute to the understanding of complex biological systems. In this ...
Brian J. Holden, John W. Pinney, Simon C. Lovell, ...
BMCBI
2008
114views more  BMCBI 2008»
15 years 4 months ago
WSPMaker: a web tool for calculating selection pressure in proteins and domains using window-sliding
Background: In the study of adaptive evolution, it is important to detect the protein coding sites where natural selection is acting. In general, the ratio of the rate of non-syno...
Yong Seok Lee, Tae-Hyung Kim, Tae-Wook Kang, Won-H...
ENTCS
2006
112views more  ENTCS 2006»
15 years 4 months ago
A Petri-Net Based Reflective Framework for the Evolution of Dynamic Systems
Nowadays, software evolution is a very hot topic. Many applications need to be updated or extended with new characteristics during their lifecycle. Software evolution is character...
Lorenzo Capra, Walter Cazzola