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NAR
2008
115views more  NAR 2008»
15 years 4 months ago
Data growth and its impact on the SCOP database: new developments
The Structural Classification of Proteins (SCOP) database is a comprehensive ordering of all proteins of known structure, according to their evolutionary and structural relationsh...
Antonina Andreeva, Dave Howorth, John-Marc Chandon...
GPEM
2007
119views more  GPEM 2007»
15 years 4 months ago
Genomic mining for complex disease traits with "random chemistry"
Our rapidly growing knowledge regarding genetic variation in the human genome offers great potential for understanding the genetic etiology of disease. This, in turn, could revolut...
Margaret J. Eppstein, Joshua L. Payne, Bill C. Whi...
NAR
2006
177views more  NAR 2006»
15 years 4 months ago
PUMA2 - grid-based high-throughput analysis of genomes and metabolic pathways
The PUMA2 system (available at http://compbio.mcs. 10 anl.gov/puma2) is an interactive, integrated bioinformatics environment for high-throughput genetic sequence analysis and met...
Natalia Maltsev, Elizabeth M. Glass, Dinanath Sula...
BMCBI
2004
126views more  BMCBI 2004»
15 years 4 months ago
A probabilistic model for the evolution of RNA structure
Background: For the purposes of finding and aligning noncoding RNA gene- and cis-regulatory elements in multiple-genome datasets, it is useful to be able to derive multi-sequence ...
Ian Holmes
GECCO
2009
Springer
131views Optimization» more  GECCO 2009»
15 years 2 months ago
A multi-objective approach to data sharing with privacy constraints and preference based objectives
Public data sharing is utilized in a number of businesses to facilitate the exchange of information. Privacy constraints are usually enforced to prevent unwanted inference of info...
Rinku Dewri, Darrell Whitley, Indrajit Ray, Indrak...