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BMCBI
2006
159views more  BMCBI 2006»
15 years 4 months ago
EVEREST: automatic identification and classification of protein domains in all protein sequences
Background: Proteins are comprised of one or several building blocks, known as domains. Such domains can be classified into families according to their evolutionary origin. Wherea...
Elon Portugaly, Amir Harel, Nathan Linial, Michal ...
BMCBI
2006
115views more  BMCBI 2006»
15 years 4 months ago
Detecting recombination in evolving nucleotide sequences
Background: Genetic recombination can produce heterogeneous phylogenetic histories within a set of homologous genes. These recombination events can be obscured by subsequent resid...
Cheong Xin Chan, Robert G. Beiko, Mark A. Ragan
160
Voted
BMCBI
2005
106views more  BMCBI 2005»
15 years 4 months ago
SIMPROT: Using an empirically determined indel distribution in simulations of protein evolution
Background: General protein evolution models help determine the baseline expectations for the evolution of sequences, and they have been extensively useful in sequence analysis an...
Andy Pang, Andrew D. Smith, Paulo A. S. Nuin, Elis...
BMCBI
2011
14 years 8 months ago
Estimation of allele frequency and association mapping using next-generation sequencing data
Background: Estimation of allele frequency is of fundamental importance in population genetic analyses and in association mapping. In most studies using next-generation sequencing...
Su Yeon Kim, Kirk E. Lohmueller, Anders Albrechtse...
107
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CCGRID
2006
IEEE
15 years 10 months ago
Grid-User Driven Grid Research, The CoBRA Grid
A new multi-purpose LightWeight Grid system (LWG) is introduced, under the acronym CoBRA grid (Computational Basic Reprogrammable Adaptive grid). It provides the functionality gri...
Peter Hellinckx, Gunther Stuer, Wouter Hendrickx, ...