4167 search results - page 761 / 834 » Evolutionary functional testing |
124
click to vote
BMCBI
2010
14 years 12 months ago
2010
Background: As the size of the known human interactome grows, biologists increasingly rely on computational tools to identify patterns that represent protein complexes and pathway...
BMCBI
2008
14 years 12 months ago
2008
Background: We propose a statistically principled baseline correction method, derived from a parametric smoothing model. It uses a score function to describe the key features of b...
BMCBI
2010
14 years 12 months ago
2010
Background: Conserved gene clusters are groups of genes that are located close to one another in the genomes of several species. They tend to code for proteins that have a functio...
BMCBI
2008
14 years 12 months ago
2008
Background: Linear motifs (LMs) are abundant short regulatory sites used for modulating the functions of many eukaryotic proteins. They play important roles in post-translational ...
BMCBI
2007
14 years 12 months ago
2007
Background: The study of the functional role of alternative splice isoforms of a gene is a very active area of research in biology. The difficulty of the experimental approach (in...