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BMCBI
2010
104views more  BMCBI 2010»
14 years 9 months ago
Parameters for accurate genome alignment
Background: Genome sequence alignments form the basis of much research. Genome alignment depends on various mundane but critical choices, such as how to mask repeats and which sco...
Martin C. Frith, Michiaki Hamada, Paul Horton
BMCBI
2010
118views more  BMCBI 2010»
14 years 9 months ago
Towards realistic benchmarks for multiple alignments of non-coding sequences
Background: With the continued development of new computational tools for multiple sequence alignment, it is necessary today to develop benchmarks that aid the selection of the mo...
Jaebum Kim, Saurabh Sinha
BMCBI
2008
179views more  BMCBI 2008»
14 years 9 months ago
Bayesian modeling of recombination events in bacterial populations
Background: We consider the discovery of recombinant segments jointly with their origins within multilocus DNA sequences from bacteria representing heterogeneous populations of fa...
Pekka Marttinen, Adam Baldwin, William P. Hanage, ...
BMCBI
2008
80views more  BMCBI 2008»
14 years 9 months ago
Towards an automatic classification of protein structural domains based on structural similarity
Background: Formal classification of a large collection of protein structures aids the understanding of evolutionary relationships among them. Classifications involving manual ste...
Vichetra Sam, Chin-Hsien Tai, Jean Garnier, Jean-F...
CORR
2008
Springer
156views Education» more  CORR 2008»
14 years 9 months ago
Artificial Immune Systems (AIS) - A New Paradigm for Heuristic Decision Making
Over the last few years, more and more heuristic decision making techniques have been inspired by nature, e.g. evolutionary algorithms, ant colony optimisation and simulated annea...
Uwe Aickelin